Henry is a precocious young boy, conceived in a petri-dish, raised by his single mother, Patricia, and is smarter than all of his peers. However, the one question he can't answer is, who is his father? Henry's attempts at locating his father lead him to Dr. Slavkin O'Hara, a university professor who has decided to raise his daughter, Audrey, as a psychology experiment in a world free of gender bias. Patricia starts fearing that she's losing her son, Audrey wishes she didn't have a father, Dr. O'Hara has no idea how to keep his daughter happy, and Henry may just have found the family he was looking for.

Based on several of the "Molly; An American Girl" books, this story is set in 1943 in the fictional town of Jefferson, Illinois during World War II. Molly McIntire and her family are learning to cope with the changes the war has brought to their close-knit family. Molly misses her father who went overseas to care for the wounded soldiers. As they try to keep things running smoothly, Molly enters a dance contest at school. She and her friends are lively, outgoing and always bursting with ideas. Also during this time a young girl named Emily comes from London England to live with the family and Molly learns the importance of getting along and pulling together.